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CRx Magazine
March/April 2023
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Editor's E-Note

A new study by University College London and King’s College London researchers, published in Addiction, reveals not only that vaporized cannabis produces the same effect on adolescents and adults but also that CBD doesn’t mitigate the effects.

In addition to reading our e-newsletter, be sure to visit CRx’s website at www.CRxmag.com.

— Kate Jackson, editor
In This E-Newsletter
E-News Exclusive
Cannabis Affects Youth and Adults Equally

The short-term effects of vaporized cannabis do not differ between adolescents and adults, while CBD does not dampen the effects of the drug, finds a new study led by University College London (UCL) and King’s College London researchers.

For the experimental study published in Addiction, the researchers measured how regular cannabis users of different ages responded to inhaling cannabis with differing levels of CBD.

The study participants included 24 adolescents (16 to 17 years old) and 24 adults (26 to 29 years old), all of whom were already regular users of cannabis (0.5 to three days per week, averaging 1.5 days of cannabis use per week).

In a clinical research facility (Invicro), the participants inhaled three types of vaporized cannabis under close medical supervision. On three separate weeks, participants were given either a placebo, or a strain of cannabis high in THC (the main psychoactive component, which typically predominates in both illegal and legal markets), or a high-CBD and high-THC version (consisting of the same level of THC, and also containing CBD). They were administered in doses comparable with typical recreational use.

FULL STORY
Other Cannabis News
Questions About Cannabis Use Should Be Part of Presurgery Screening
The American Society of Regional Anesthesia and Pain Medicine has released the first US guidelines on cannabis use in relation to surgery, calling for anesthesiologists to ask patients undergoing surgical procedures about their cannabis use, to be prepared to change the surgical game plan, and to counsel patients about the risks and effects of cannabis.

Increasing Popularity of Cannabis for Chronic Pain
A new study published in JAMA Network Open shows that nearly one-third of patients with chronic pain use cannabis to relieve their pain. The researchers surveyed 1,724 adults, more than one-half of whom decreased the use of pain medications after using cannabis. The findings, says lead author Mark Bicket, MD, PhD, point to the need for research into the risks and rewards of cannabis for chronic pain.

How Cannabis and the Oral Microbiome Affect the Brain
For several years, Wei Jiang, MD, has been studying the way cannabis smoking changes the oral microbiome. Now, with funding from the National Institute on Drug Abuse, the Medical University of South Carolina professor of microbiology and immunology, with collaborator Sylvia Fitting, PhD, is studying the influence of those changes on neurological disease.

A Primer on CBD Tea
Medical News Today reports on the uses, pros, and cons of CBD tea, noting the lack of substantial studies to back up manufacturer claims.
Products and Services
Standardized Credential Programs for Cannabis Professionals
To meet the demands of the industry, HACC, Central Pennsylvania’s Community College, has partnered with Green Flower, an on-demand training platform built for cannabis professionals, to offer three new certificate training programs to provide job skills for people interested in a cannabis career. The eight-week online programs advance skills for retail, cultivation, and manufacturing professionals. Learn more »

When Medicinal CBD Is a Lifesaver
Mighty Flower: How Cannabis Saved My Son, by Annabelle Manolo-Morgan, PhD, a cell and developmental biologist, details the difficult treatment choices the author had to make after her newborn experienced seizures—for which the only treatment was the removal of part of his brain—and her research into the use of CBD to help prevent the developmental challenges such treatment would cause. Learn more »
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